Cocaine interactions on FDA labels
These are pairs with Cocaine where an FDA label names an interaction, grouped by the desk's grade. A drug that isn't listed here hasn't been cleared as safe with Cocaine; it just isn't on this list. Open any pair in the desk to see it alongside other drugs.
Avoid together
- Cocaine and Phenelzine
Why this grade
Nardil (phenelzine) label, Contraindications
The Nardil (phenelzine) label lists this combination under Contraindications. CONTRAINDICATIONS: "patients being treated with NARDIL should not take sympathomimetic drugs (including … cocaine" Named in the label: "cocaine" Retrieved from DailyMed 2026-10-12.
Open source
Enzyme roles on the desk
- CYP3A4 · minor-pathway substrate
Educational reference only. Not FDA-cleared. The Prescribing Information governs.
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