Buprenorphine and Ethanol

Desk tier: Serious concern

Mechanism: alcohol × CNS depressant (additive CNS depression)

“the concomitant use of benzodiazepines or other CNS depressants, including alcohol, increases the risk of respiratory depression, profound sedation, coma, and death”

Suboxone (buprenorphine/naloxone) film, section 7 DRUG INTERACTIONS (Benzodiazepines and Other CNS Depressants). DailyMed label

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All pairs for Buprenorphine · Ethanol

Educational reference only. Not FDA-cleared. The Prescribing Information governs.