Eletriptan and troleandomycin
Desk tier: Avoid together
Mechanism: labeled contraindication (labeled contraindication)
“Recent use (i.e., within at least 72 hours) of the following potent CYP3A4 inhibitors: ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, or nelfinavir”
Why this grade
Relpax (eletriptan) label, Contraindications
The Relpax (eletriptan) label lists this combination under Contraindications. 4 CONTRAINDICATIONS: "Recent use (i.e., within at least 72 hours) of the following potent CYP3A4 inhibitors: ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, or nelfinavir" Named in the label: "troleandomycin" Retrieved from DailyMed 2026-10-12.
Relpax (eletriptan) label on DailyMedAll pairs for Eletriptan · troleandomycin
Educational reference only. Not FDA-cleared. The Prescribing Information governs.
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