Esketamine and Phenelzine

Desk tier: Use care

Mechanism: washout clock (lingering perpetrator effect)

“Concomitant use with monoamine oxidase inhibitors (MAOIs) may increase blood pressure … Closely monitor blood pressure with concomitant use of SPRAVATO with MAOIs.”

Spravato (esketamine), section 7.3 Monoamine Oxidase Inhibitors (MAOIs); 5.7. DailyMed label

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All pairs for Esketamine · Phenelzine

Educational reference only. Not FDA-cleared. The Prescribing Information governs.