Isocarboxazid and Tyramine foods

Desk tier: Avoid together

Mechanism: tyramine × MAOI (hypertensive crisis)

“Marplan (isocarboxazid) should not be administered in combination with any of the following: … cheese or other foods with a high tyramine content”

Marplan (isocarboxazid), section CONTRAINDICATIONS. DailyMed label

Why this grade

Marplan (isocarboxazid) label, Contraindications

The Marplan (isocarboxazid) label lists this combination under Contraindications. CONTRAINDICATIONS: "Marplan (isocarboxazid) should not be administered in combination with any of the following: … cheese or other foods with a high tyramine content" Named in the label: "cheese or other foods with a high tyramine content" Retrieved from DailyMed 2026-10-19.

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Educational reference only. Not FDA-cleared. The Prescribing Information governs.

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