Itraconazole and Methylergonovine
Desk tier: Avoid together
Mechanism: strong CYP3A4 inhibition of clearance (↑ exposure)
“Coadministration of a number of CYP3A4 substrates are contraindicated with SPORANOX®.”
All pairs for Itraconazole · Methylergonovine
Enzyme behind this pair: CYP3A4
Educational reference only. Not FDA-cleared. The Prescribing Information governs.