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Ivabradine and Clarithromycin

Desk tier: Avoid together

Mechanism: strong CYP3A4 inhibition of clearance (↑ exposure)

“Concomitant use of strong cytochrome P450 3A4 (CYP3A4) inhibitors”
Corlanor (ivabradine), section 4 CONTRAINDICATIONS. DailyMed label

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All pairs for Ivabradine · Clarithromycin

Enzyme behind this pair: CYP3A4

Educational reference only. Not FDA-cleared. The Prescribing Information governs.