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Ketamine and Ethanol

Desk tier: Serious concern

Mechanism: NMDA dissociative × CNS depressant (additive CNS depression)

“Concomitant use of ketamine with … other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death”
Ketalar (ketamine), section 7.3 Benzodiazepines, Opioid Analgesics, Or Other CNS Depressants; 5.9. DailyMed label

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All pairs for Ketamine · Ethanol

Educational reference only. Not FDA-cleared. The Prescribing Information governs.