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Ketamine and Theophylline

Desk tier: Use care

Mechanism: stacked proconvulsant effect (lowered seizure threshold)

“Concomitant administration of KETALAR and theophylline or aminophylline may lower the seizure threshold. Consider using an alternative to KETALAR in patients receiving theophylline or aminophylline.”
Ketalar (ketamine), section 7.1 Theophylline or Aminophylline. DailyMed label

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All pairs for Ketamine · Theophylline

Educational reference only. Not FDA-cleared. The Prescribing Information governs.