Levoketoconazole and Dofetilide
Desk tier: Avoid together
Mechanism: labeled contraindication (labeled contraindication)
“Concomitant use of RECORLEV with other drugs that cause QT prolongation associated with ventricular arrhythmias, including torsades de pointes, is contraindicated”
Why this grade
Recorlev (levoketoconazole) label, Contraindications
The Recorlev (levoketoconazole) label lists this combination under Contraindications. Contraindications: "RECORLEV is contraindicated in patients: … Taking drugs that cause QT prolongation associated with ventricular arrhythmias, including torsades de pointes" 7.1 Effect of RECORLEV on Other Drugs (Table 6): "Concomitant use of RECORLEV with other drugs that cause QT prolongation associated with ventricular arrhythmias, including torsades de pointes, is contraindicated" Named in the label: "dofetilide" Retrieved from DailyMed 2026-10-05.
Open sourceAll pairs for Levoketoconazole · Dofetilide
Educational reference only. Not FDA-cleared. The Prescribing Information governs.
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