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Levoketoconazole and Dofetilide

Desk tier: Avoid together

Mechanism: labeled contraindication (labeled contraindication)

“Concomitant use of RECORLEV with other drugs that cause QT prolongation associated with ventricular arrhythmias, including torsades de pointes, is contraindicated”
Recorlev (levoketoconazole), section 7.1 Effect of RECORLEV on Other Drugs (Table 6). DailyMed label
Why this grade

Recorlev (levoketoconazole) label, Contraindications

The Recorlev (levoketoconazole) label lists this combination under Contraindications. Contraindications: "RECORLEV is contraindicated in patients: … Taking drugs that cause QT prolongation associated with ventricular arrhythmias, including torsades de pointes" 7.1 Effect of RECORLEV on Other Drugs (Table 6): "Concomitant use of RECORLEV with other drugs that cause QT prolongation associated with ventricular arrhythmias, including torsades de pointes, is contraindicated" Named in the label: "dofetilide" Retrieved from DailyMed 2026-10-05.

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All pairs for Levoketoconazole · Dofetilide

Educational reference only. Not FDA-cleared. The Prescribing Information governs.

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