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Lurasidone and Rifampin

Desk tier: Avoid together

Mechanism: strong CYP3A4 induction of clearance (↓ exposure / loss of efficacy)

“Strong CYP3A4 inducers (e.g., rifampin, avasimibe, St. John's wort, phenytoin, carbamazepine, etc.)”
Latuda (lurasidone), section 4 CONTRAINDICATIONS. DailyMed label

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All pairs for Lurasidone · Rifampin

Enzyme behind this pair: CYP3A4

Educational reference only. Not FDA-cleared. The Prescribing Information governs.