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Milnacipran and Methylene blue

Desk tier: Avoid together

Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)

“Starting SAVELLA in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated”
Savella (milnacipran), section 4.1 Monoamine Oxidase Inhibitors (MAOIs). DailyMed label

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All pairs for Milnacipran · Methylene blue

Educational reference only. Not FDA-cleared. The Prescribing Information governs.