Phenelzine and Dopamine

Desk tier: Avoid together

Mechanism: MAOI × stimulant (hypertensive crisis)

“patients being treated with NARDIL should not take sympathomimetic drugs (including … dopamine”

Nardil (phenelzine), section CONTRAINDICATIONS. DailyMed label

Why this grade

Nardil (phenelzine) label, Contraindications

The Nardil (phenelzine) label lists this combination under Contraindications. CONTRAINDICATIONS: "patients being treated with NARDIL should not take sympathomimetic drugs (including … dopamine" Named in the label: "dopamine" Retrieved from DailyMed 2026-10-12.

Open source

FDA boxed / safety communication

Amphetamine and methylphenidate labels contraindicate use during or within 14 days after an MAOI (hypertensive crisis). Cocaine, MDMA, and other unlabeled stimulants are the desk extending that label; open the PI.

Open source

PMID 12925718

2003 QJM. Dunkley. Clonus, hyperreflexia, hyperthermia. The teaching screen.

Open source

Open this pair in the desk

All pairs for Phenelzine · Dopamine

Educational reference only. Not FDA-cleared. The Prescribing Information governs.

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