All pairs

Phenelzine and Fluoxetine

Desk tier: Avoid together

Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)

“The use of MAOIs intended to treat psychiatric disorders with PROZAC or within 5 weeks of stopping treatment with PROZAC is contraindicated”
Prozac (fluoxetine), section 4.1 Monoamine Oxidase Inhibitors (MAOIs). DailyMed label

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All pairs for Phenelzine · Fluoxetine

Educational reference only. Not FDA-cleared. The Prescribing Information governs.