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Pimozide and Fluvoxamine

Desk tier: Avoid together

Mechanism: moderate CYP3A4 inhibition of clearance (↑ exposure)

“Coadministration of tizanidine, thioridazine, alosetron, or pimozide with Fluvoxamine Maleate Tablets is contraindicated”
Fluvoxamine maleate tablets, section 4 CONTRAINDICATIONS. DailyMed label

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All pairs for Pimozide · Fluvoxamine

Enzyme behind this pair: CYP3A4

Educational reference only. Not FDA-cleared. The Prescribing Information governs.