All pairs

Ramelteon and Fluvoxamine

Desk tier: Avoid together

Mechanism: strong CYP1A2 inhibition of clearance (↑ exposure)

“Patients should not take ROZEREM in conjunction with fluvoxamine”
Rozerem (ramelteon), section 4 CONTRAINDICATIONS. DailyMed label

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All pairs for Ramelteon · Fluvoxamine

Enzyme behind this pair: CYP1A2

Educational reference only. Not FDA-cleared. The Prescribing Information governs.