All pairs

Ranolazine and Rifampin

Desk tier: Avoid together

Mechanism: strong CYP3A4 induction of clearance (↓ exposure / loss of efficacy)

“Do not use RANEXA with CYP3A inducers such as rifampin, rifabutin, rifapentine, phenobarbital, phenytoin, carbamazepine”
Ranexa (ranolazine), section 7.1 (see 4 CONTRAINDICATIONS). DailyMed label

Open this pair in the desk

All pairs for Ranolazine · Rifampin

Enzyme behind this pair: CYP3A4

Educational reference only. Not FDA-cleared. The Prescribing Information governs.