Safinamide and Linezolid
Desk tier: Avoid together
Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)
“XADAGO is contraindicated in patients with: Concomitant use of other drugs in the monoamine oxidase inhibitor (MAOI) class … including linezolid”
All pairs for Safinamide · Linezolid
Educational reference only. Not FDA-cleared. The Prescribing Information governs.