Sertraline and Linezolid

Desk tier: Avoid together

Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)

“ZOLOFT is contraindicated in patients: … Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue)”

Zoloft (sertraline), section 4 CONTRAINDICATIONS. DailyMed label

Open this pair in the desk

All pairs for Sertraline · Linezolid

Educational reference only. Not FDA-cleared. The Prescribing Information governs.