Trazodone and Linezolid

Desk tier: Avoid together

Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)

“Patients taking, or within 14 days of stopping, monoamine oxidase inhibitors (MAOIs), including MAOIs such as linezolid or intravenous methylene blue”

Trazodone hydrochloride tablets, section 4 CONTRAINDICATIONS. DailyMed label

Open this pair in the desk

All pairs for Trazodone · Linezolid

Educational reference only. Not FDA-cleared. The Prescribing Information governs.