Trazodone and Methylene blue
Desk tier: Avoid together
Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)
“Patients taking, or within 14 days of stopping, monoamine oxidase inhibitors (MAOIs), including MAOIs such as linezolid or intravenous methylene blue”
All pairs for Trazodone · Methylene blue
Educational reference only. Not FDA-cleared. The Prescribing Information governs.