Venlafaxine and Methylene blue

Desk tier: Avoid together

Mechanism: MAOI × serotonergic (serotonin syndrome / hypertensive crisis)

“Effexor XR is contraindicated in patients: … taking, or within 14 days of stopping, MAOIs (including the MAOIs linezolid and intravenous methylene blue)”

Effexor XR (venlafaxine), section 4 CONTRAINDICATIONS. DailyMed label

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All pairs for Venlafaxine · Methylene blue

Educational reference only. Not FDA-cleared. The Prescribing Information governs.