Zolpidem interactions on FDA labels
These are pairs with Zolpidem where an FDA label names an interaction, grouped by the desk's grade. A drug that isn't listed here hasn't been cleared as safe with Zolpidem; it just isn't on this list. Open any pair in the desk to see it alongside other drugs.
Avoid together
- Zolpidem and Sodium oxybate
Why this grade
Xyrem (sodium oxybate) label, 4 CONTRAINDICATIONS
The Xyrem (sodium oxybate) label calls this combination contraindicated: "Xyrem is contraindicated for use in: •combination with sedative hypnotics" Retrieved from DailyMed 2026-09-27.
Open source
Enzyme roles on the desk
- CYP3A4 · major-pathway substrate
Educational reference only. Not FDA-cleared. The Prescribing Information governs.
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