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Carbamazepine and Nefazodone

Desk tier: Avoid together

Mechanism: strong CYP3A4 induction of clearance (↓ exposure / loss of efficacy)

“Coadministration of carbamazepine with nefazodone is contraindicated.”
Tegretol (carbamazepine), section CONTRAINDICATIONS. DailyMed label

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All pairs for Carbamazepine · Nefazodone

Enzyme behind this pair: CYP3A4

Educational reference only. Not FDA-cleared. The Prescribing Information governs.