Eletriptan and Nefazodone

Desk tier: Avoid together

Mechanism: strong CYP3A4 inhibition of clearance (↑ exposure)

“Recent use (i.e., within at least 72 hours) of the following potent CYP3A4 inhibitors: ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, or nelfinavir”

Relpax (eletriptan), section 4 CONTRAINDICATIONS. DailyMed label

Open this pair in the desk

All pairs for Eletriptan · Nefazodone

Enzyme behind this pair: CYP3A4

Educational reference only. Not FDA-cleared. The Prescribing Information governs.