All pairs

Naltrexone and Oxycodone

Desk tier: Avoid together

Mechanism: opioid antagonist × agonist (precipitated withdrawal / blocked analgesia)

“Naltrexone hydrochloride is contraindicated in: … Patients receiving opioid analgesics.”
Naltrexone HCl tablets, section CONTRAINDICATIONS. DailyMed label

Open this pair in the desk

All pairs for Naltrexone · Oxycodone

Educational reference only. Not FDA-cleared. The Prescribing Information governs.