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Nefazodone and terfenadine

Desk tier: Avoid together

Mechanism: labeled contraindication (labeled contraindication)

“Coadministration of terfenadine, astemizole, cisapride, pimozide, or carbamazepine with nefazodone hydrochloride is contraindicated”
Nefazodone, section Contraindications. DailyMed label
Why this grade

Nefazodone label, Contraindications

The Nefazodone label lists this combination under Contraindications. Contraindications: "Coadministration of terfenadine, astemizole, cisapride, pimozide, or carbamazepine with nefazodone hydrochloride is contraindicated" Named in the label: "terfenadine" Retrieved from DailyMed 2026-10-02.

Nefazodone label on DailyMed

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All pairs for Nefazodone · terfenadine

Educational reference only. Not FDA-cleared. The Prescribing Information governs.

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