Erythromycin interactions on FDA labels
These are pairs with Erythromycin where an FDA label names an interaction, grouped by the desk's grade. A drug that isn't listed here hasn't been cleared as safe with Erythromycin; it just isn't on this list. Open any pair in the desk to see it alongside other drugs.
Avoid together
- Erythromycin and Dihydroergotamine
Why this grade
Dihydroergotamine mesylate injection label, Contraindications
The Dihydroergotamine mesylate injection label lists this combination under Contraindications. CONTRAINDICATIONS: "The use of potent CYP3A4 inhibitors (i.e., ritonavir, nelfinavir, indinavir, erythromycin, clarithromycin, troleandomycin, ketoconazole, itraconazole) with dihydroergotamine is, therefore contraindicated" Named in the label: "erythromycin" Retrieved from DailyMed 2026-10-12.
Open source - Erythromycin and Dronedarone
Why this grade
Multaq (dronedarone) label, Contraindications
The Multaq (dronedarone) label lists this combination under Contraindications. 4 CONTRAINDICATIONS: "MULTAQ is contraindicated in patients with: … Concomitant use of erythromycin" Named in the label: "erythromycin" Retrieved from DailyMed 2026-10-12.
Open source - Erythromycin and Ergotamine
Why this grade
Cafergot (ergotamine/caffeine) label, Contraindications
The Cafergot (ergotamine/caffeine) label lists this combination under Contraindications. CONTRAINDICATIONS: "Coadministration of ergotamine with potent CYP 3A4 inhibitors (ritonavir, nelfinavir, indinavir, erythromycin, clarithromycin, and troleandomycin) … ergotamine use is contraindicated with these drugs" Named in the label: "erythromycin" Retrieved from DailyMed 2026-10-12.
Open source - Erythromycin and Pimozide
Why this grade
Pimozide label, Contraindications
The Pimozide label lists this combination under Contraindications. CONTRAINDICATIONS: "pimozide is contraindicated in patients receiving the macrolide antibiotics clarithromycin, erythromycin, azithromycin, dirithromycin, and troleandomycin" Named in the label: "erythromycin" Retrieved from DailyMed 2026-10-12.
Open source
Enzyme roles on the desk
Educational reference only. Not FDA-cleared. The Prescribing Information governs.
Drug and product names are trademarks of their owners and are used only to identify the products.