St. John's wort interactions on FDA labels
These are pairs with St. John's wort where an FDA label names an interaction, grouped by the desk's grade. A drug that isn't listed here hasn't been cleared as safe with St. John's wort; it just isn't on this list. Open any pair in the desk to see it alongside other drugs.
Open St. John's wort in the desk
Avoid together
- St. John's wort and Atazanavir
- St. John's wort and Atazanavir–cobicistat
- St. John's wort and Darunavir
- St. John's wort and Darunavir–cobicistat
- St. John's wort and Lopinavir/ritonavir
- St. John's wort and Lurasidone
- St. John's wort and Paxlovid (nirmatrelvir/ritonavir)
- St. John's wort and Ranolazine
- St. John's wort and Rasagiline
- St. John's wort and Rilpivirine
- St. John's wort and Ritonavir
- St. John's wort and Safinamide
Enzyme roles on the desk
Educational reference only. Not FDA-cleared. The Prescribing Information governs.